Stereospecific ligands and their complexes - Part XIV: Crystal structure of O,O’-dipropyl ester of (S,S)-ethylenediamine-N,N’-di-2-(4-methyl)-pentanoic acid dihydrochloride

Synthesis, Characterization, and Cytotoxicity of a Novel Gold(III) Complex with O,O’-Diethyl Ester of Ethylenediamine-N,N’-Di-2-(4-Methyl)Pentanoic Acid

A novel gold(III) complex, [AuCl2{(S,S)-Et2eddl}]PF6, ((S,S)-Et2eddl = O,O′-diethyl ester of ethylenediamine-N,N′-di-2-(4-methyl)pentanoic acid) was synthesized and characterized by IR, 1D (1H and 13C), and 2D (H,H-COSY and H,H-NOESY) NMR spectroscopy, mass spectrometry, and elemental analysis. Density functional theory calculations confirmed that (R,R)-N,N′ diastereoisomer was energetically th...

5-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-yl)-2-methyl-pentanoic Acid Methyl Ester

A natural diastereomeric mixture of 5-(6-hydroxy-2,5,7,8-tetramethyl-chroman2-yl)-2-methyl-pentanoic acid methyl ester (1), was isolated from the soft coral Sinularia arborea. The structure of 1 was elucidated by spectroscopic methods and 1 displayed a significantly inhibitory effect on the generation of superoxide anion by human neutrophils.

Crystal structure of 2-[N-(t-butoxycarbonyl)amino]-4-(thymin-1-yl)-butyric acid methyl ester.

psuedopeptide backbone composed of N-(2-aminoethyl) glycine units, and nucleobases are attached by methylene carbonyl linkers (Fig. 1). Since the binding of PNA to DNA inhibits transcription, the potential of PNA has been focused to target an antisense drug.1 Moreover, PNA-peptides hybridization and improvements of the PNA backbone unit were developed to form DNA-DNA-PNA triplexes with nonspeci...

Ii Nn Ss Tt Rr Uu Cc Tt Ii Oo Nn Ss Ff Oo Rr Uu Ss E

Synthesis, Crystal Structure and Antibacterial Evaluation of Di-μ-chlorido-bis({2-[(4-methoxyphenyl)- iminomethyl]pyridine-κ2N,N']Mercury(II)

New coordination polymer of [HgLCl2]n (1) with HgCl2 and Schiff base bidentate ligand (4-methoxyphenyl) pyridine-2yl methyleneamine (L) was prepared and structurally characterized. In the 1D network structure of 1, the mecury (II) ion adopts an HgN2Cl3 distorted square pyramid geometry. In this complex, one of the chlorine acts as bridging ligand connecting two adjacent mercury(II) ions while, ...